Volume : 3, Issue : 6, JUN 2017

ANTIBACTERIAL POTENTIAL OF LEAF EXTRACTS OF XANTHIUM STRUMARIUM L. AGAINST MULTI-DRUG RESISTANT E. COLI & STAPH. AUREUS.

JENI R. PATEL, DR. T. G. GOHIL

Abstract

The antibacterial activity of leaf extract of Xanthium strumarium Lin. belonging to family Asteraceae was evaluated in-vitro against most common multi-drug resistant clinical isolate Escherichia coli and Staphylococcus aureus by disc diffusion and agar-well diffusion method. Two solvents chloroform and methanol were used for extraction of bioactive compound from fresh leaves. The yield (%) of crude extract was 5.4 % and 6.3 % respectively. Antimicrobial potential of leaf extract was determined by measuring the zone of inhibition. It was concluded from the results that methanolic as well as chloroform extracts of leaf of Xanthium strumarium were quite effective in inhibiting the growth of E. coli and Staphylococcus aureus which is a serious human pathogen of UTI and wound infection. Decoction – Hot aqueous extraction also supported the antibacterial potential of this plant. Result also revealed that chloroform extract has more antibacterial potential than methanolic extract against Staphylococcus aureus. Therefore, the leaf extracts of this plant can be selected for further investigation to determine their therapeutic potential.

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